Research and Development – Philippine Institute of Pure and Applied Chemistry

A vital part of PIPAC’s package of services is basic and applied research conducted independently or in cooperation with client companies.

Institute Personnel and their Research Interests

- - Armando Victor M. Guidote, Jr., Ph.D.
    Research Interests:
    Organic Chemistry, Natural Products, Chemistry Education
    Click here to see the list of his publications.
  - Armando Jerome H. de Jesus, Jr., Ph.D.
    Research Interests:
    Molecular dynamics simulations, Membrane-protein interactions, Membrane protein-small molecule interactions
    Click here to see the list of his publications.
  - Ronaldo M. Fabicon, Ph.D.
    Research Interests:
    Industrial Chemistry
    Click here to see the list of his publications.
  - Crisanto M. Lopez, Dr.rer.nat
    Research Interests:
    Infection Biology, Fungal Biotechnology
    Click here to see the list of his publications.
  - Giselle Grace F. Lim-Co Yu Kang, Ph.D
    Research Interests:
    Biochemistry, Enzymes, Analytical Chemistry
    Click here to see the list of her publications.
  - Gilbert U. Yu, D.Eng
    Research Interests:
    Materials Science (Polymers and Supramolecules), Chemical Education, Development of Lab Experiment Modules
    Click here to see the list of his publications.
  - Ian Ken D. Dimzon, Ph.D
    Research Interests:
    Applied Analytical Chemistry, Mass Spectrometry, Chemical Metrology
    Click here to see the list of his publications.
  - Anna Carissa M. San Esteban, Ph.D
    Research Interests:
    Electrochemistry (corrosion, electrocatalytic processes); Coordination Chemistry (coordination polymers, metal-organic frameworks)
    Click here to see the list of her publications.

Selected Publications

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2011

Ma. Henrietta Olmos-Dela Cruz; Rene Angelo S. Macahig; Mailyn M. Terrado; Henson L. Lee Yu; Armando M. Guidote Jr.; Joselito P. Quirino

Biomarkers of Asthma: Recent Patents from 2009-2011 Journal Article

In: Recent Patents on Biomarkers, vol. 2, no. 1, pp. 54-59, 2011, ISSN: 2210-3104.

Abstract | Links | Tags: asthma, biomarkers, bronchoalveolar lavage proteins, diagnosis, exhaled biomarkers, mast cell stability, metabolites, proteins, serum inflammatory biomarkers, small molecules

@article{DelaCruz2011,

title = {Biomarkers of Asthma: Recent Patents from 2009-2011},

author = {Ma. Henrietta Olmos-Dela Cruz and Rene Angelo S. Macahig and Mailyn M. Terrado and Henson L. Lee Yu and Armando M. Guidote Jr. and Joselito P. Quirino},

url = {https://www.eurekaselect.com/94950/article},

doi = {10.2174/2210309011202010054},

issn = {2210-3104},

year  = {2011},

date = {2011-09-26},

journal = {Recent Patents on Biomarkers},

volume = {2},

number = {1},

pages = {54-59},

abstract = {This review informs on current literature on patents for biomarkers for asthma from 2009 to 2011. Variable airflow obstruction in asthma is generally triggered by gene-environment interactions that can lead to key symptoms of cough, shortness of breath, chest tightness, and wheezing. The episodic and variable degrees of airway hyperresponsiveness arise from a variety of inflammatory pathways that can make diagnosis and management difficult. Standard pulmonary function tests used for the diagnosis of asthma may fail to predict individual responses to the standard bronchodilator and corticosteroid therapies. Phenotypic predispositions can alter the severity of the asthmatic condition and treatment response. Biomarkers from sputum, exhaled gases, exhaled breath condensates, urine, serum, and broncheolaveolar fluid lavage proteins are currently explored to provide objective metrics for identifying individuals at risk, provide therapy guidance, monitor disease progression and evaluate response to therapy, as a supplement to standard pulmonary function tests. Updates on the refinement of technologies, inherent limitations and benefits of these biomarkers are discussed to provide insights on how current understanding of pathologic mechanisms has been applied to provide information for addressing gaps in the diagnosis and management of asthma.},

keywords = {asthma, biomarkers, bronchoalveolar lavage proteins, diagnosis, exhaled biomarkers, mast cell stability, metabolites, proteins, serum inflammatory biomarkers, small molecules},

pubstate = {published},

tppubtype = {article}

}